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Pharmacogenomic
Services
Your Source for Pharmacogenomic,
Biomarker and Mutation Discovery Research |
At TRANSGENOMIC, we bring discoveries to life. Working as an extension of your team and partner in clinical trial support, together we can help you open windows of discovery that translates into understanding disease, biomarkers and drug development providing effective therapeutics, diagnostics and healthier lives.
| MUTATION DETECTION |
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SUPERIOR TECHNOLOGY
Featuring our WAVE® Mutation Detection System and SURVEYOR® Nuclease.
UNPARALLELED SENSITIVITY
Our proven expertise and technology detect heterozygous mutations with a sensitivity of 99.5%.
HIGHEST SPECIFICITY
Of all reported mutations, novel variants and de novo mutations including splice-donor site mutations and deletions, germline parental mosaicisms and incomplete penetrance. |
| Our sensitivity and technology easily detect
low-level mutations in cancer pathway genes not detected by sequencing
alone. |
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Figure A. WAVE DHPLC analysis provides
robust results detecting alleles as low as 0.5% in cancer pathway genes.
Figure B. Same analysis by sequencing shows a lack of mutant allele
detection which typically requires much higher levels and a detection
limit of 30-40%. |
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| Cancer-related mutations easily missed as background
noise are detected with our sensitive technology. |
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| BIOMARKER DEVELOPMENT
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ANY GENE — ANY ORGANISM — ANY SAMPLE
Whether it’s human, viruses, DNA, RNA, blood, or FFPE tissue our experts can find what others miss.GENES AND DISEASE ANALYSIS
Methylation Analysis
Micro-RNA Analysis
Pathway Analysis
Biomarker Discovery
Translational Research
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| ASSAY DESIGN AND VALIDATION |
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CUSTOMIZED
Assays designed specifically for your projects or chose from our
portfolio of hundreds of in-house developed assays.
FAST
Our rapid assay development and validation is among the industry’s
fastest providing results when you need them.
CONSULTING SERVICES
Count on our expert staff and experience to advise you on how to
customize your experimental approach and protocols to best meet your
requirements and deliverables. |
When Finding the Gene Matters
For questions or to discuss a new project,
contact our professionals at 240-631-2001.
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